Dublin Office: +353 1 460 7600 | Cork Office: +353 21 233 9410
Dublin Office: +353 1 460 7600 | Cork Office: +353 21 233 9410
Single Use Components for Pharmaceutical & Biopharmaceutical Manufacturing
NexSus provides high-quality Single Use Components designed to support every stage of the bioprocessing lifecycle. Working with leading global manufacturing partners, we deliver customised solutions that improve fluid management, reduce contamination risk and integrate seamlessly into pharmaceutical and biotechnology production environments. Whether you’re developing a new process, scaling production or optimising an existing operation, our team works closely with you to design fluid paths and component assemblies tailored to your specific application.
Our technical specialists combine application expertise with a consultative approach to help identify the right components for your process. From fluid path design and custom assemblies to manufacturing process support, we deliver solutions that improve operational efficiency, maintain product integrity and support regulatory compliance. With access to a comprehensive portfolio of Single Use technologies, NexSus helps manufacturers implement flexible, scalable systems that perform reliably in even the most demanding environments.
Whether you require standard components or a fully bespoke solution, NexSus is your trusted partner for Single Use Systems, providing the technical expertise, global partnerships and local support needed to help your manufacturing processes operate with confidence.
Single-use sanitary instrument fittings that maintain a sterile barrier while allowing the use of standard reusable pressure instruments.
NexSus supplies aSURE™ Instrument Tees for accurate pressure monitoring in hybrid and fully single-use process lines. A fused elastomeric diaphragm isolates the process fluid from the instrument, creating a continuous aseptic barrier without solvents or adhesives. The platform allows customers to retain established pressure gauges, transmitters and calibration programmes rather than adopting a proprietary disposable sensor architecture.
Typical applications:
TFF feed, retentate and permeate monitoring; multi-stage depth filtration; bioreactor pressure monitoring; chromatography; centrifugation and downstream filtration; perfusion; DMSO-compatible process lines.
Multi-layer single-use pillow bags from 250 mL to 50 L for the storage, transfer and handling of biopharmaceutical process fluids.
NexSus provides Flex4Sure™ 2D Bags for small- and medium-volume storage, transfer, sampling and intermediate-hold applications. The RENOLIT INFUFLEX 9101 film platform combines visual clarity, low gas permeability, physical strength and broad biocompatibility, with customised ports, tubing, filters and distal connectors available to suit the process.
Typical applications:
Media and buffer storage; sample collection and transport; purified-component collection; temporary intermediate hold; drug-substance storage and transfer; end-product transport.
Large-volume 100 L to 1,000 L single-use bag-in-box systems for storage and transfer of biopharmaceutical process solutions.
NexSus supplies Flex4Sure™ 3D Bags for large-volume buffer, media, intermediate and drug-substance handling. The bag systems use RENOLIT INFUFLEX 9101 multi-layer film and are engineered to fit a range of market-leading cubical totes, helping customers integrate an alternative bag platform without unnecessary hardware replacement.
Typical applications:
Buffer and media storage and transport; harvested-cell-culture-fluid transfer; purified-component collection; intermediate storage after filtration; drug-substance storage and transfer.
Sterile, closed centrifuge-tube assemblies for aseptic sampling, transfer and controlled recovery of small process volumes.
NexSus supplies Cap2V8® Centrifuge Tube Assemblies to replace manual tube filling and sampling steps with a closed, pre-sterilised fluid path. One-piece moulded closures combine tubing, feed and vent paths with standard centrifuge tubes, helping reduce contamination risk, assembly time and cleaning requirements.
Typical applications:
Aseptic process sampling; cell-culture and fermentation samples; pilot and process development; vaccine production; sterile transfer; pellet isolation and small-volume collection.
One-piece moulded sterile closures for Gibco media bottles, creating a closed fluid path for media transfer and laboratory processing.
NexSus provides Cap2V8® closures for Gibco™ media bottles to convert familiar laboratory containers into closed, ready-to-use transfer assemblies. The unitised cap-and-tube design reduces manual connections and supports sterile feed, vent and optional multi-port configurations.
Typical applications:
Tissue and cell-culture media; process development; laboratory research; media transfer; aseptic sampling.
Autoclavable one-piece closure assemblies that add a closed feed-and-vent path to existing GL45 glass bottles.
NexSus supplies Cap2V8® GL45 closures for customers who want to retain reusable glass bottles while simplifying sterile fluid transfer. The moulded polypropylene cap and integrated tubing create a continuous aseptic path and can be customised with dip tubes, vent filters, sterile connectors and alternative tubing.
Typical applications:
Laboratory and process research; tissue and cell-culture media; fermentation; aseptic sampling; vaccine production; sterile transfer and filling.
Sterile cap-and-bottle assemblies for Nalgene® media bottles from 60 mL to 2 L.
NexSus supplies Cap2V8® Nalgene® Bottle Assemblies for closed storage, transfer and sampling using widely adopted square and round media bottles. The one-piece moulded closure eliminates adhesive joints and combines feed, dip and vent functions into a pre-sterilised assembly.
Typical applications:
Cell-culture media; fermentation; process development; laboratory research; aseptic sampling; vaccine production; sterile filling and transfer.
Closed, sterile rigid-container assemblies combining PharmaTainer bottles, moulded Cap2V8 closures and configurable tubing.
NexSus supplies standard and custom Cap2V8® PharmaTainer™ assemblies for aseptic storage, sampling, transfer and filling. The unitised, adhesive-free closure creates one continuous fluid path and can be configured with dip tubes, sample ports, sterile connectors, filters and process-specific tubing.
Typical applications:
Media and buffer handling; cell-culture and fermentation; pilot and process development; aseptic sampling; vaccine manufacture; sterile transfer and filling.
Sterile two- or three-port closure assemblies for Corning and Nalge shaker flasks used in cell-culture and process-development workflows.
NexSus supplies Cap2V8® Shaker Flask Assemblies to create a closed feed, transfer and sampling path on commonly used shaker flasks. Standard moulded closures are available for selected Corning and Nalge formats, with tubing, port count, dip-tube geometry and accessories configurable to the application.
Typical applications:
Cell culture; inoculum expansion; pilot and process development; laboratory research; sterile transfer.
High-security non-metallic pinch clamps for critical tubing and reinforced-hose applications.
NexSus supplies Bio-Ease+™ HD Pinch Clamps for applications where secure shut-off, repeatability and regulatory compliance are essential. The heavy-duty glass-filled nylon design provides higher-pressure capability and greater security than a standard pinch clamp while remaining lightweight, corrosion resistant and suitable for metal-free assemblies.
Typical applications:
Single-use transfer lines; pharma and biopharma manufacturing; reinforced hose isolation; research laboratories; metal-free fluid paths.
Patented non-metallic sanitary clamps for secure ASME-BPE and BPSA flange connections.
NexSus supplies Bio-Ease+™ sanitary clamps as a lightweight, corrosion-resistant alternative to stainless-steel hygienic clamps. The floating-hinge and limited-slip design self-adjusts to provide balanced contact pressure while reducing the risk of damaging non-metallic ferrules.
Typical applications:
Single-use systems; pharma and biopharma transfer lines; laboratories; metal-incompatible applications; sanitary flange connections.
Compact non-metallic sanitary clamps for securing mini and 1.5-inch single-use hygienic connections.
NexSus supplies SaniSure® Clamps for simple, lightweight closure of selected sanitary ferrules in single-use assemblies. Their low-mass nylon construction supports clean, corrosion-resistant fluid-path designs and can be incorporated into custom assemblies.
Typical applications:
Single-use transfer lines; bottle and bag assemblies; sanitary process connections; laboratory and production fluid paths.
Threaded PVDF clamps for secure True Union and selected Sani-Pro sanitary connections.
NexSus supplies True Union Clamps where a compact threaded non-metallic connection is required. The PVDF construction provides chemical resistance and a robust mechanical closure for compatible fitting geometries.
Typical applications:
Single-use and hybrid process lines; chemical-resistant transfer systems; Sani-Pro fitting connections; sanitary equipment interfaces.
Ready-made and fully customised single-use 316L filling needles for clinical and commercial fill-finish equipment.
NexSus supplies Fill4Sure™ Filling Needles for customers seeking an alternative to restrictive OEM needle designs. Standard and made-to-fit formats support automated and benchtop filling, with attention to filling speed, accuracy, repeatability, machine fit and product sensitivity.
Typical applications:
Automated final fill for drug products; cell and gene therapy; formulation filling; clinical-trial benchtop filling; gas-overlay filling for oxygen-sensitive products.
A broad portfolio of medical-grade non-metallic fittings, adapters and process components for single-use fluid-path design.
NexSus provides access to an extensive range of sanitary fittings and hard-to-find single-use components for building complete bioprocess assemblies. The portfolio supports sanitary, hose-barb, monobarb and specialist transition requirements across multiple materials, helping customers standardise complex fluid paths from a single technical source.
Typical applications:
Media and buffer transfer; upstream and downstream assemblies; filtration; sampling; filling; equipment connections; hose and manifold construction.
Compact PVDF stir bars for maintaining media, buffers and process solutions in suspension within single-use bags and rigid containers.
NexSus supplies Gamma-Stable Stir Bars for applications where conventional mixers may be unnecessarily complex or potentially harmful to sensitive cells. The low-profile PVDF design can be inserted through selected hose barbs and used in bottles, carboys, bags, flasks and other biopharmaceutical containers.
Typical applications:
Media and buffer preparation; process purification; cell-culture bioreactors; fermentation and harvest; formulation; final fill.
A closed, top-mounted single-use mixing system for low-shear through vigorous mixing in 5 L to 50 L rigid containers.
NexSus supplies Mixed4Sure™ Top Mount for customers requiring enclosed rigid-container mixing without a conventional bottom stir bar. A magnetically coupled suspended Pronto impeller is positioned above the container base, reducing surface contact and particulate-generation risk while supporting a wide range of mixing intensity.
Typical applications:
Media and buffer preparation; reagent mixing; process intermediates; formulation; cell and gene therapy process fluids; closed rigid-container mixing.
Whether you’re looking for technical guidance, product information or support with your Single Use Systems requirements, our team is here to help.
Speak to a specialist or request a consultation
+353 1 460 7600
customerservice@lennox.ie
+353 21 233 9410
customerservice@lennox.ie
